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Optimizing Brain Health: The DUTCH Plus Test

The DUTCH Plus Test for ADHD, Autism, Sleep, Mood and Hormonal Balance

DUTCH Hormone Assessment
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Unlock the Power of Precision Testing for Better Mental Health

At Sanctum Healthcare, we believe in uncovering the full picture of your health. The DUTCH Plus Test offers cutting-edge insights into how hormones, stress, and metabolism impact brain health, ADHD, autism, sleep, mood and histamine sensitivity. By integrating scientific precision and a holistic approach, we help you achieve clarity and balance in your health journey

Why the DUTCH Plus Test?

This test provides a 24-hour comprehensive view of your body’s hormonal and metabolic function—essential for uncovering the root causes of conditions like ADHD, autism, poor sleep, mood dysregulation and hormonal imbalances.

The DUTCH Plus combines urine and saliva testing to evaluate:

Hormone Testing Diagram

Key Features of the DUTCH Plus Test

1. Convenient At-Home Testing: Collect urine and saliva samples from the comfort of home.

2. Comprehensive Insights: Measures 35+ markers to provide a full picture of hormonal, stress, and neurological health.

3. Personalized Analysis: Each result is interpreted within your unique health context to guide tailored interventions.

The Sanctum brain health approach in a map
At Sanctum Healthcare, we view ADHD and Autism as integral parts of overall brain health, where cognitive, emotional, behavioural and physical factors intersect. Understanding that symptoms of ADHD and Autism are often influenced by underlying root causes such as stress, sleep disturbances, hormonal imbalances, and lifestyle factors, we utilise cutting-edge tools like the DUTCH Plus Test to gain deeper insights into these connections.
This allows us to explore the unique biochemical and hormonal factors contributing to each individual’s challenges. This holistic perspective ensures that we address not just symptoms, but the root causes of dysfunction, enabling us to craft tailored strategies that optimise brain health and empower individuals to thrive.
Wellness Score via Sanctum app
Female Sex Hormones Diagram
App metrics and scoring via Sanctum App
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Result markers via Sanctum App

Key Features of the DUTCH Plus Test

1. Convenient At-Home Testing:

Collect urine and saliva samples from the comfort of home.
2. Comprehensive Insights:

Measures 35+ markers to provide a full picture of hormonal, stress, and neurological health.

3. Personalized Analysis:
Each result is interpreted within your unique health context to guide tailored interventions.

Personalized Bespoke Report

The DUTCH Plus result can be transformed into a tailored report that includes:

• Comprehensive Analysis: Hormone, cortisol, melatonin, and neurotransmitter markers.

• Symptom Correlation: Relating results to your challenges like fatigue, ADHD, mood swings, or sleep issues.

• Actionable Recommendations:

o Stress management (mindfulness, adaptogens)

o Sleep support (melatonin therapy, sleep hygiene)

o Hormonal balance (dietary changes, supplements)

o Gut-brain health (probiotics, organic acid insights)

How it works?

Empowering Your Health Journey

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Step Description

1. Order the Test Choose between Test-Only or Test + Consultation.

2. Receive the Kit Samples are collected at home.

3. Send to Lab Return the samples directly to our lab.

4. Expert Analysis Our specialists interpret results for ADHD, autism, sleep, and mood.

5. Receive Bespoke Plan Detailed report and consultation with actionable strategies.

Invest in Personalised Insights for Better Health Outcomes

Choose between our Test Only option, providing raw data for those who prefer independent analysis, or our Test + Interpretative Report, which includes expert evaluation and personalised recommendations tailored to your unique needs.
Dutch Plus Test

£320

Test + Report

£619

Impact of hormonal fluctuations on symptoms

Meet Dr Raffi from Sanctum Healthcare

"CBT for insomnia works, when followed and executed properly. We want solid data and we will make it much more accurate by using the best in class wearable device"

Founder– Dr Asad Raffi

Start Your Journey to Clarity and Understanding

Take the first step towards understanding yourself or your loved one with our tailored assessment process. Completing this form helps us gather essential information to provide you with personalised insights and support. Whether you’re exploring ADHD, Autism, or their overlap, our expert-led assessments are designed to empower you with clarity and guidance for the next steps in your journey to improved brain health and wellbeing.

Contact Us Today to Learn More and Join Our Team

Be a better version of yourself with the help of Sanctum Healthcare

Achieve your true potential by managing your ADHD

Sanctum Healthcare

3, The Beeches, Beech Lane, Wilmslow, SK9 5ER

TEL: 0161 768 7634
Opening Hours: Mon-Fri 0900-1700

We’re here to help answer any questions you have about the assessment process

Hormone Testing Diagram
Hormone Testing
The DUTCH Plus® test provides a comprehensive evaluation of your hormone health, offering invaluable insights into how your body functions daily. By measuring critical factors such as the Cortisol Awakening Response (CAR), melatonin levels, sex hormones, and organic acids, it paints a detailed picture of your hormonal balance and overall well-being. With this information, we can identify specific imbalances—whether minor shifts or major conditions like PCOS or thyroid disorders—and create a tailored lifestyle and supplement protocol just for you. This test empowers you with the confidence to make informed decisions and take control of your health.

Hormonal and Metabolic Profiling

Hormonal and Metabolic Profiling

The DUTCH Plus Test is an advanced hormone, stress, and metabolic assessment that uses urine and saliva samples to provide a comprehensive view of:

• Sex hormones: Estrogen, progesterone, testosterone, and their metabolites.

• Cortisol patterns: Including the Cortisol Awakening Response (CAR) for stress assessment.

• Melatonin production: For sleep regulation.

• Neurotransmitter markers: Such as dopamine and serotonin precursors.

• Gut and oxidative stress markers: Assessing inflammation and gut-brain health.

The DUTCH Plus Test is ideal for individuals experiencing:

• ADHD and autism: Poor focus, brain fog and emotional dysregulation.

• Sleep disturbances: Insomnia, restless sleep, or daytime fatigue.

• Hormonal imbalances: PMS, perimenopause, menopause, or low testosterone.

• Chronic stress and burnout: Cortisol dysregulation leading to fatigue, anxiety and mood swings.

• Mood disorders: Depression, anxiety, or irritability.

• Histamine hypersensitivity: Symptoms like headaches, brain fog, and inflammation caused by estrogen dominance or oxidative stress.

The test is easy and convenient:

1. At-Home Collection: You’ll collect 4 dried urine samples and 5 saliva samples at specific times throughout the day.

2. Cortisol Awakening Response (CAR): Saliva samples are collected at waking, 30 minutes, and 60 minutes after waking.

3. Send to Lab: Once complete, samples are sent back to our lab for analysis.

4. Personalized Report: Results are provided within 10-14 days, including an in-depth analysis and tailored health recommendations.

The DUTCH Plus Test is ideal for individuals experiencing:

• ADHD and autism: Poor focus, brain fog and emotional dysregulation.

• Sleep disturbances: Insomnia, restless sleep, or daytime fatigue.

• Hormonal imbalances: PMS, perimenopause, menopause, or low testosterone.

• Chronic stress and burnout: Cortisol dysregulation leading to fatigue, anxiety and mood swings.

• Mood disorders: Depression, anxiety, or irritability.

• Histamine hypersensitivity: Symptoms like headaches, brain fog, and inflammation caused by estrogen dominance or oxidative stress.

During your first visit, you will undergo a comprehensive assessment with one of our mental health professionals. This session will involve discussing your symptoms, medical history, and any concerns you may have. The CAR evaluates your body’s cortisol production immediately after waking, offering insights into how your body responds to stress. • Elevated CAR: May indicate acute stress, anxiety, or hyperactivity of the HPA axis. • Blunted CAR: Suggests burnout, chronic fatigue, PTSD, or sleep disorders. This is critical for identifying subtle cortisol imbalances and early stress-related dysfunction.

The DUTCH Plus Test identifies the physiological factors influencing ADHD and autism, including:

• Hormonal fluctuations: Low estrogen or testosterone affecting dopamine production and focus.

• Cortisol dysregulation: Stress patterns that exacerbate hyperactivity, impulsivity and fatigue.

• Neurotransmitter imbalances: Low dopamine and serotonin contributing to poor focus and mood swings.

• Melatonin disruption: Causing sleep difficulties common in neurodivergent individuals.

These insights help guide personalized strategies for improved focus, emotional balance, and sleep

Sleep disturbances often result from hormonal or stress-related imbalances:

• Low melatonin: Disrupts sleep onset and quality.

• High nighttime cortisol: Prevents relaxation and deep sleep.

• Blunted morning cortisol: Causes daytime fatigue and grogginess.

The DUTCH Plus identifies these imbalances, enabling targeted interventions like melatonin support, stress management strategies, and sleep hygiene improvements.

Hormonal imbalances and stress dysregulation are often linked to mood swings, irritability, and anxiety: • Estrogen and progesterone: Affect mood and emotional stability, particularly during PMS, perimenopause, or menopause. • Cortisol: Chronic stress disrupts neurotransmitter balance, impacting mood regulation. • Dopamine and serotonin markers: Help identify neurotransmitter deficiencies that influence mood and focus. By addressing these imbalances, the DUTCH Plus Test provides insights to improve emotional resilience and mental well-being.
Estrogen can stimulate histamine release, which may trigger symptoms like: • Headaches • Brain fog • Fatigue • Inflammation The DUTCH Plus Test evaluates estrogen metabolites, oxidative stress markers, and gut health to pinpoint the root causes of histamine sensitivity and guide targeted interventions like dietary changes and anti-inflammatory support.
Results are typically available within 10-14 business days from the time the lab receives your samples. You’ll receive a detailed Bespoke Report and have the option to schedule a consultation to review the findings and personalized recommendations should you chose this option.

Your Bespoke Report includes:

• Comprehensive Analysis: Hormones, cortisol, melatonin, and neurotransmitter results.

• Symptom Correlation: Explaining how results relate to your specific symptoms.

• Personalized Recommendations:

o Stress management strategies

o Hormonal balance solutions

o Sleep optimization techniques

o Gut-brain health support

• Actionable Steps: Tailored interventions to improve focus, mood, sleep, and overall well-being.

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3 The Beeches, Wilmslow SK9 5ER
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